TSCA Activity Tracker (2025–26)
2025—26 TSCA Activity Tracker
Latest on TSCA Risk Evaluations and New Regulations
Recent updates from US EPA affecting chemical risk management regulations, evaluation of chemical risks, and/or priortiziation of chemicals for evaluation as mandated by the Toxic Substances Control Act (TSCA), as amended.Latest TSCA Chemical Risk Evaluation Updates
- EPA completed the final risk evaluation for 1,3-butadiene, finding it poses an unreasonable risk to health under 12 conditions of use.
- EPA is preparing to reconsider the 2024 Final Rule to prohibit or restrict uses of perchloroethylene (PCE), and is seeking public comments
- EPA extended the deadline for manufacturers to submit health and safety data on 16 high priority chemicals, until May 22, 2026.
What Are TSCA Chemical Risk Evaluations?
The Toxic Substance Control Act (TSCA), as amended, directs US EPA to evaluate the risks of chemicals on the TSCA Inventory and address any “unreasonable risks” with regulations to restrict manufacturing, distribution, and/or use.Lion tracks the risk evaluation and rulemaking process here—from prioritization of a chemical through publication of risk management standards under TSCA Section 6, when applicable. This page also highlights key dates for industry stakeholders who wish to participate in the chemical risk evaluation and rulemaking process by submitting comments, attending public meetings, etc.
Use the orange tabs above to explore the latest TSCA chemical risk management rules, track risk evaluations as they are drafted and finalized, and look ahead at which chemicals are up next for evaluation.
Past Updates
- EPA postponed the compliance date for workplace chemical protections for non-prohibited uses of TCE, until February 17, 2026
- EPA announced the availability of Draft Risk Evaluations for two phthalates, butyl benzyl phthalate (BBP) and diisobutyl phthalate (DIBP)
- EPA announced that the final Risk Evaluation for 1,1-dichloroethane is available
- EPA delayed the effective date for specific provisions in the TCE Final Rule until August 19, 2025
- EPA will accept comments on draft risk evaluations for two phthalates, DBP and DEHP, until August 4, 2025.
- EPA extended the deadline for chemical manufacturers to submit health and safety data for 16 substances until May 22, 2026
- EPA extended the comment period for the draft risk evaluation of DCHP until May 9.
- EPA re-opened the comment period for the proposed rule to add worker protections for PV29 in powder form until April 29
- EPA extended the comment period for the draft scope of a risk evaluation for vinyl chloride until April 2
- EPA extended the comment period for the draft risk evaluation of 1,3-butadiene until March 5
- EPA delayed the effective date of the Final Rule for the chemical trichloroethylene (TCE) until March 21
- EPA issued a supplement to the Draft Risk Evaluation for 1,3-butadiene and is extending the comment period until March 25
Final Rules
When a risk evaluation shows a that chemical poses an “unreasonable risk” to human health or the environment, EPA must act to address the risk(s) with regulations for manufacturing, distribution, and/or use of the substance.
| Chemical name | Effective Date | See 40 CFR 751... | Link to Final Rule |
|---|---|---|---|
| Trichloroethylene (TCE) | 03/21/25 (*)(†) | Subpart D (751.301—.325) | Update (9/17/25) |
| Carbon Tetrachloride (CTC) | 01/17/25 (**) | Subpart H (751.701—.713) | Update (9/17/25) |
| Perchloroethylene (PCE) | 01/17/25 (***) | Subpart G (751.601—.617) | Update (07/30/25) |
| Methylene Chloride (MCL) | 07/08/24 | Subpart B (751.101—.117) | Final Rule (05/08/24) |
| Asbestos (Chrysotile) | 05/28/24 | Subpart F (751.501—.515) | Final Rule (03/28/24) |
* Trichloroethylene (TCE). US EPA has postponed—until February 17, 2026—the deadline for compliance with requirements for monitoring and controlling exposure for exempted uses of TCE under TSCA §6(a).
† Trichloroethylene (TCE). US EPA has extended the compliance deadlines for two conditions of use for TCE, including use as a processing aid in the manufacture of nuclear fuel.
** Carbon Tetrachloride (CTC). EPA announced on September 12, 2025 that the 2024 Final Rule for carbon tetrachloride or "carbon tet" will be reconsidered in response to legal challenges.
*** Perchloroethylene (PCE). EPA is preparing to reconsider the December 2024 Final Rule to prohibit or restrict uses of PCE. On July 30, 2025, the Agency requested comments from stakeholders and the public to inform that effort.
Final Rules for PBT Chemicals
Section 6(h) of TSCA directs US EPA to evaluate and, if necessary, address the risks posed by specific persistent, bioaccumulative, and toxic chemical substances or "PBTs".
| Chemical name | Latest Update | See 40 CFR 751... |
|---|---|---|
| Decabromodiphenyl ether (DecaBDE) | Final Rule—Revisions (11/19/24) | Subpart E (751.405) |
| Phenol, Isopropylated Phosphate 3:1 (PIP 3:1) | Final Rule—Revisions (11/19/24) | Subpart E (751.407) |
| Pentachlorothiophenol (PCTP) | Final Rule (01/06/21) | Subpart E (751.411) |
| Hexachlorobutadiene (HCBD) | Final Rule (01/06/21) | Subpart E (751.413) |
| 2,4,6-tris(tert-butyl)phenol (2,4,6- TTBP) | Final Rule (01/06/21) | Subpart E (751.409) |
Proposed Rules
EPA follows strict procedure to impose new TSCA restrictions. The process involves talking with stakeholders, proposing a rule, taking comments, and having the rule approved by the Office of Management and Budget (OMB).
| Chemical name | Comments End | Rule Details | Link to Proposed Rule |
|---|---|---|---|
| C.I. Pigment Violet 29 (PV-29) | Details | Comments Extended | |
| 1-bromopropane (1-BP) | Details | Proposed Rule | |
| n-Methylpyrrolidone (NMP) | Details | Proposed Rule |
Proposed Rules for PBT Chemicals
Section 6(h) of TSCA directs US EPA to evaluate and, if necessary, address the risks posed by specific persistent, bioaccumulative, and toxic chemical substances or "PBTs".
| Chemical name | Comments End | Link to Proposed Rule |
|---|---|---|
| Phenol, Isopropylated Phosphate 3:1 (PIP 3:1) | Final Rule published 11/19/24 | |
| Decabromodiphenyl ether (DecaBDE) | Final Rule published 11/19/24 | |
Final Risk Evaluations
After reviewing and addressing public comments, EPA announces the result of each risk evaluation along with a final determination concerning “unreasonable risk.” Completed evaluations will be listed below until EPA takes further action.
| Chemical name | Announced | Unreasonable Risk? | Link to Notice |
|---|---|---|---|
| 1,3-butadiene | 12/30/25 | Yes (Health) | Final Risk Evaluation |
| 1,1-dichloroethane (1,1-DCA) | 06/23/25 | Yes (Health) | Final Risk Evaluation |
| Di-isononyl phthalate (DINP) * | 01/14/25 | Yes (Health) | Final Risk Evaluation |
| Formaldehyde | 01/03/25 (**) | Yes (Health) | Update (12/2025) |
| Asbestos (Legacy Uses/Disposals) | 11/27/24 | Yes (Health) | Final Risk Evaluation |
| 1,4-dioxane | 11/14/24 | Yes (Health) | Final Risk Evaluation |
| Tris(2-chloroethyl) phosphate (TCEP) | 09/26/24 | Yes (Health, Environment) | Final Risk Evaluation |
| HBCD 1 | 06/29/22 | Yes (Health, Environment) | Rev. Risk Evaluation |
* Manufacturer requested risk evaluation
** In December 2025, EPA announced the availability of an Updated Draft Risk Calculation Memorandum for formaldehyde, and will accept public comments until February 2, 2026
1 a.k.a. Cyclic Aliphatic Bromide Cluster
Draft Risk Evaluations
Before acting on the results of a risk evaluation, EPA must share the evaluation in draft form. At this stage, stakeholders and the public can review and comment on EPA’s findings before a final determination is made.
| Chemical name | Comments End | Unreasonable Risk? | Link to Notice |
|---|---|---|---|
| 1,2-dichloroethane (Ethylene dichloride) | 01/20/26 | Yes (Health, Environment) | Draft Risk Evaluation |
| Octamethylcyclotetrasiloxane (D4) * | Yes (Health, Environment) | Notice | |
| Di-isobutyl phthalate (DIBP) | Yes (Health, Environment) | Notice | |
| Butyl benzyl phthalate (BBP) | Yes (Health, Environment | Notice | |
| Dibutyl phthalate (DBP) | Yes (Health, Environment) | Notice | |
| Diethylhexyl phthalate (DEHP) | Yes (Health, Environment) | Notice | |
| Dicyclohexyl phthalate (DCHP) | Yes (Health) | Comments Extended | |
| Di-iosdecyl phthalate (DIDP) * | Yes (Health) | Notice |
* Manufacturer requested risk evaluation
High Priority Chemicals
To identify chemicals as “high priority” for risk evaluation, EPA draws mostly from a TSCA Work Plan completed in 2014. EPA also considers public comments, available scientific data, and statutory requirement/limits.
| Chemical name | Comments End | Designated | Link |
|---|---|---|---|
| Vinyl Chloride | 12/18/24 | Update | |
| 4-tert-Ocylphenol | 12/18/24 (Proposed) | Notice | |
| Benzene | 12/18/24 (Proposed) | Notice | |
| Ethylbenzene | 12/18/24 (Proposed) | Notice | |
| Naphthalene | 12/18/24 (Proposed) | Notice | |
| Styrene | 12/18/24 (Proposed) | Notice | |
| Acetaldehyde | 12/18/24 | Notice | |
| Acrylonitrile | 12/18/24 | Notice | |
| Benzenamine | 12/18/24 | Notice | |
| MBOCA 3 | 12/18/24 | Notice | |
| 1,3-butadiene | - | 12/20/19 | Final Scope |
| Dibutyl phthalate (DBP) | - | 12/20/19 | Final Scope |
| o-Dichlorobenzene | - | 12/20/19 | Final Scope |
| p-Dichlorobenzene | - | 12/20/19 | Final Scope |
| trans-1,2-Dichloroethylene | - | 12/20/19 | Final Scope |
| 1,2-Dichloropropane | - | 12/20/19 | Final Scope |
| Di-ethylhexyl phthalate (DEHP) | - | 12/20/19 | Final Scope |
| Ethylene dibromide | - | 12/20/19 | Final Scope |
| HHCB 2 | - | 12/20/19 | Final Scope |
| TBBPA 1 | - | 12/20/19 | Final Scope |
| Phosphoric acid, triphenyl ester (TPP) | - | 12/20/19 | Final Scope |
| Phthalic anhydride | - | 12/20/19 | Final Scope |
| 1,1,2-Trichloroethane | - | 12/20/19 | Final Scope |
* Manufacturer-requested Risk Evaluation
1 4,4'-(1-Methylethylidene)bis[2, 6-dibromophenol] [TBBPA]
2 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta [g]-2-benzopyran [HHCB]
3 '4-4'-methylene bis(2-chloroaniline) [MBOCA]
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